Court of Appeal refuses leave to appeal — the direct-appeal route ends

The Court of Appeal (Criminal Division) refuses leave to appeal the original Letby convictions on the specific grounds then advanced. The refusal is decided on the evidence then available to the Court — which did not include the Shoo Lee Panel report (February 2025), the Joint Insulin Report (May 2025), the paediatric-pathology re-readings (October 2025), the Thirlwall Inquiry evidence (2024-2026), or any of the post-2024 expert material. The CCRC route under section 13 of the Criminal Appeal Act 1995 remains open, and the Donna Anthony precedent (2005) establishes it is not foreclosed by a first-appeal refusal.